News
Study reveals genetic signatures linked to HIV-related cognitive impairment
1+ hour, 57+ min ago (334+ words) Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled....
Polyamines reshape protein phosphorylation to guide key cellular fate decisions
2+ hour, 1+ min ago (516+ words) Polyamines reshape protein phosphorylation to guide key cellular fate decisions'News-Medical Polyamines reshape protein phosphorylation to guide key cellular fate decisions Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an alteration in…...
ACROBiosystem's PE-Labeled Human BCMA / TNFRSF17 Protein, His Tag (Site-specific conjugation)
17+ hour, 56+ min ago (371+ words) ACRO's PE-Labeled Human BCMA, His Tag (BCA-HP2H2) is manufactured via site-specific conjugation of PE to Human BCMA, His Tag. TNFRSF17, CD269, BCM, BCMA The PE-Labeled Human BCMA, His Tag (BCA-HP2H2) is generated through a site-specific conjugation of PE to Human BCMA, His…...
Novel antibody shows promise in overcoming resistance to cancer immunotherapy
1+ day, 1+ hour ago (350+ words) According to a Phase I study led by researchers at The University of Texas MD'Anderson Cancer Center, published today in Nature Medicine, the novel monoclonal antibody linavonkibart demonstrated the potential to overcome treatment resistance to anti-PD-1 immune checkpoint inhibitors in…...
Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial
1+ day, 1+ hour ago (725+ words) Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial'News-Medical Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising results…...
Cat disease research reveals coronavirus's broad attack on the immune system
1+ day, 16+ hour ago (531+ words) Researchers at the University of California, Davis, have uncovered new details about how a once-deadly coronavirus disease in cats spreads through the immune system. The findings may help scientists better understand long COVID and other long-lasting inflammatory illnesses in people....
Two harmful gene variants can combine to restore normal protein function
2+ day, 1+ hour ago (295+ words) Two harmful gene variants can combine to restore normal protein function'News-Medical Two harmful gene variants can combine to restore normal protein function In a groundbreaking study published in the in Proceedings of the National Academy of Sciences (PNAS), scientists at…...
ALS breakthrough: Restoring protein production in motor neuron axons
2+ day, 16+ hour ago (383+ words) Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS). ALS breakthrough: Restoring protein production in motor neuron axons Researchers at VIB…...
Key protein in the tuberculosis bacterium helps protect itself from foreign DNA
5+ day, 9+ hour ago (352+ words) "This protein is interesting to study as it controls a large set of genes in the bacteria," says Mahipal Ganji, Assistant Professor at the Department of Biochemistry, IISc, and corresponding author of the study. In the current study, the team…...
Targeting IDO1 for cancer: Novel degraders show promise in preclinical studies
5+ day, 10+ hour ago (183+ words) About 130 years ago, American physician William Coley injected a terminally ill cancer patient with a lethal cocktail of bacteria directly into his tumour. The patient developed a high fever and, miraculously, the tumour completely regressed. Cancer immunotherapy " the use of…...