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News
These Protein Pops Sold Out in 8 Hours. It’s Easy to See Why
2+ hour, 48+ min ago (22+ words) These popular snacks are hitting stores nationwide soon....
AI Uncovers Hidden Human Protein That Builds Bridges Between Cells
11+ min ago (679+ words) For most of modern biology, the hunt for new human proteins has followed a familiar path: read the genetic sequence, predict where genes begin and end, and work outward from there. That strategy has served science remarkably well, delivering the…...
Heart cells can ‘remember’ stress and use it for protection during chemotherapy
4+ hour, 39+ min ago (1157+ words) Early stress in mitochondria before birth helped mouse hearts resist later chemotherapy damage by creating lasting protective changes. Chemotherapy can save lives, but some drugs can also put the heart under serious strain. Doxorubicin, a chemotherapy used against several cancers,…...
PROTACs Move From Lab Concept to Clinical Reality in Targeted Protein
55+ min ago (746+ words) A sweeping new review published in Discover Chemistry charts the remarkable rise of proteolysis-targeting chimeras, better known as PROTACs, from a bold theoretical idea to one of the most closely watched platforms in modern drug discovery. Written by Sandip G....
Tea Catechins Transform Waste Rice Bran into Powerful Emulsion Stabilizers
57+ min ago (55+ words) Rice bran, the fibrous outer layer stripped away when brown rice is polished into white rice, is produced at a staggering scale of more than 63 million tons every year. Most of it is pressed for its oil, but what remains…...
One Amino Acid Decides Whether Mitochondria Keep Their Protein Machines
1+ hour, 9+ min ago (75+ words) Mitochondria are the power stations of the cell, but they are also among the most dependent organelles in biology. The vast majority of the roughly one thousand proteins that make up a working mitochondrion are manufactured outside the organelle, in…...
SOX9 Acts Early to Rewire Hippo–YAP/TAZ Signaling as Glioblastoma Cells
1+ hour, 24+ min ago (639+ words) Glioblastoma remains one of the most lethal human cancers, and much of its lethality stems from a hidden population of tumor cells that behave like stem cells, capable of self-renewal, plasticity, and resistance to therapy....
Lipid Metabolism Emerges as a Central Driver of Drug Resistance in
1+ hour, 35+ min ago (71+ words) Aggressive non-Hodgkin lymphoma remains one of the most stubborn challenges in modern hematology. Even with a therapeutic arsenal that now includes rituximab-based immunochemotherapy, targeted kinase inhibitors, immune checkpoint blockade, and chimeric antigen receptor T-cell therapies, a substantial fraction of patients…...
Scientists Discover CD55 Is the Hidden Switch That Powers Natural Killer
1+ hour, 35+ min ago (680+ words) Natural killer cells have long been celebrated as the swift, unsung assassins of the immune system, capable of detecting and destroying tumor cells without the elaborate priming that T cells require....