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Nature
nature.com > articles > s41392-025-02543-x

The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progression - Signal Transduction and Targeted Therapy

The dysadherin/carbonic anhydrase 9 axis shapes an acidic tumor microenvironment to promote colorectal cancer progression - Signal Transduction and Targeted Therapy56+ min ago   (1723+ words) An acidic TME is positively associated with dysadherin expression and contributes to CRC progression. a A list of DEGs in tumor tissue compared with normal tissue was obtained from the GEO database (GSE106582) (p" Overall, our study demonstrated that tumor cells…...

@genbio
genengnews.com > topics > translational-medicine > cryo-em-maps-autoantibody-hotspots-on-nmda-receptors-in-autoimmune-encephalitis

Cryo-EM Maps Autoantibody Hotspots on NMDA Receptors in Autoimmune Encephalitis

Cryo-EM Maps Autoantibody Hotspots on NMDA Receptors in Autoimmune Encephalitis2+ hour, 59+ min ago   (549+ words) Using near-atomic cryo-EM, scientists mapped where pathogenic autoantibodies bind to NMDA receptors in the brain, identifying hotspots that could improve diagnosis and therapies for "Brain on Fire" disorder. The post Cryo-EM Maps Autoantibody Hotspots on NMDA Receptors in Autoimmune Encephalitis…...

News-Medical
news-medical.net-medical.net

Study reveals genetic signatures linked to HIV-related cognitive impairment

Study reveals genetic signatures linked to HIV-related cognitive impairment3+ hour, 22+ min ago   (334+ words) Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled....

News-Medical
news-medical.net-medical.net

Polyamines reshape protein phosphorylation to guide key cellular fate decisions

Polyamines reshape protein phosphorylation to guide key cellular fate decisions3+ hour, 26+ min ago   (516+ words) Polyamines reshape protein phosphorylation to guide key cellular fate decisions'News-Medical Polyamines reshape protein phosphorylation to guide key cellular fate decisions Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an alteration in…...

BostonGlobe.com
bostonglobe.com > 01/14/2026 > lifestyle > red-meat-nutrition-experts

How much red meat should you eat? Here’s what nutrition experts say.

How much red meat should you eat? Here’s what nutrition experts say.3+ hour, 33+ min ago   (819+ words) How much red meat should you eat? To find out how much red meat, butter and other types of full-fat dairy are okay to include in your diet, the Washington Post asked three top nutrition experts. And if you're eating…...

Foodbeast
foodbeast.com > listicle > fast-food-is-leaning-hard-into-protein-heres-11-items-that-prove-it

Fast Food Is Leaning Hard Into Protein—Here’s 11 Items That Prove It

4+ hour, 56+ min ago   (202+ words) Fast Food Is Leaning Hard Into Protein'Here's 11 Items That Prove It'Foodbeast Yup, protein is all the rage right now. According to a YouGov study about Americans' New Year's Resolutions for 2026, 25% said they resolved to exercise more, 23% said they planned to…...

BIOENGINEER.ORG
bioengineer.org > ligand-paths-shape-cellular-gpcr-signaling

Ligand Paths Shape Cellular GPCR Signaling

Ligand Paths Shape Cellular GPCR Signaling5+ hour, 36+ min ago   (696+ words) Ligand Paths Shape Cellular GPCR Signaling'Bioengineer.org In a groundbreaking study published in Nature, researchers have unveiled the intricate molecular choreography that underlies G-protein-coupled receptor (GPCR) signaling, revealing how distinct ligands elicit unique conformational trajectories in receptor'G-protein complexes within living…...

Herald-Tribune
heraldtribune.com > press-release > story > 123806 > how-sequence-based-ai-achieve-whole-genome-screening-for-billions-of-small-molecule-and-antibody-candidates-in-hours

How sequence-based AI achieve whole genome screening for billions of small molecule and antibody candidates in hours

How sequence-based AI achieve whole genome screening for billions of small molecule and antibody candidates in hours6+ hour, 10+ min ago   (983+ words) Destructed Drug Discovery: Sequence-Based AI for Rapid Evaluation of Small Molecules and Antibodies" SAN FRANCISCO , CA, UNITED STATES, January 14, 2026 /EINPresswire.com/ " Ainnocence today announced a major milestone in artificial-intelligence driven drug discovery in the white paper by C&EN: a…...

The Hindu
thehindu.com > news > cities > bangalore > researchers-develop-ai-tool-to-predict-how-shapeshifting-proteins-connect-inside-cells > article70509429.ece

Researchers develop AI tool to predict how shapeshifting proteins connect inside cells

Researchers develop AI tool to predict how shapeshifting proteins connect inside cells6+ hour, 51+ min ago   (193+ words) Published - January 14, 2026 11:35 pm IST - Bengaluru Researchers at the National Centre for Biological Sciences (NCBS), Tata Institute of Fundamental Research, Bengaluru, have developed a deep-learning tool that can predict how intrinsically disordered proteins (IDP) latch on to their binding partners. But…...

The Independent
independent.co.uk > bulletin > news > virus-bacteria-iss-international-space-station-b2900548.html

Researchers discover viruses behave differently in space

Researchers discover viruses behave differently in space7+ hour, 53+ min ago   (137+ words) Researchers discover viruses behave differently in space'The Independent Researchers discover viruses behave differently in space - A new study has revealed that bacteria-infecting viruses appear to behave differently in space compared to on Earth, with infection being slowed. - Researchers compared E. coli…...