7+ mon, 2+ week ago  (468+ words) We find the origin of the genetic code mysteriously linked to the dipeptide composition of a proteome, the collective of proteins in an organism," said corresponding author'Gustavo Caetano-Anoll's, professor in the'Department of Crop Sciences, the Carl R. Woese'Institute for Genomic Biology,…...

3+ week, 4+ day ago  (492+ words) New peer-reviewed research in Brain Medicine demonstrates that neuronal nitric oxide synthase drives neuroblastoma through the m TOR signaling cascade, and that a selective inhibitor called BA-101 collapsed tumor growth in mice with striking force Now, a study published in…...

1+ mon, 2+ week ago  (679+ words) Amyloid beta may disrupt tau's helpful role image: Microtubules in blue, tau represented in green, and a-beta in yellow. view more New UC Riverside-led research suggests Alzheimer's arises not simply from plaques forming in the brain, as is widely believed,…...

1+ week, 3+ day ago  (472+ words) Same drivers of disease within microglia indicate that certain cancer treatments may be effective for Alzheimer's Microglia-like immune cells with cancer mutations (purple) emerge in the brain. Separately, clumps of proteins, like Tau or amyloid, accumulate in the brain, making…...

7+ mon, 3+ week ago  (291+ words) The molecule Wnt, which plays a role in cell communication during human development, evolved from a superfamily with a shared lipid-modifying mechanism originally involved in bacterial defense and immunity image: The four helices conserved across the Lipocone superfamily constitute a…...

1+ mon, 1+ week ago  (623+ words) Australian researchers have uncovered a critical mechanism driving the growth and spread of glioblastoma " one of the most aggressive and lethal forms of brain cancer " potentially paving the way for more effective treatments. In a new study led by Adelaide…...

2+ week, 2+ day ago  (152+ words) Schematic overview of an ovarian follicle-based angiogenesis microphysiological system (OF-AMPS). Growing ovarian follicles serve as self-contained angiogenic microphysiological units, enabling the rapid formation of complex 3 D vascular networks within 24 hours without exogenous VEGF. The platform supports multimodal imaging and quantitative…...

4+ mon, 3+ week ago  (153+ words) A comprehensive study published in Med Research details how the complex ecosystem surrounding immune cells drives chronic conditions'from heart disease to cancer'and points toward novel targeted therapies. The Immune Microenvironment: More Than Just Defense "Although immunity serves as the defense…...

3+ week, 5+ day ago  (390+ words) A study published in'Ageing Research Reviews'and led by MA Yinzhong's team from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences provided an integrated perspective on how glial cells contribute to disease progression through metabolic reprogramming,…...

5+ mon, 3+ week ago  (425+ words) Artificial intelligence (AI) and "protein language" models can speed the design of monoclonal antibodies that prevent or reduce the severity of potentially life-threatening viral infections, according to a multi-institutional study led by researchers at Vanderbilt University Medical Center. While their…...