1+ hour, 24+ min ago  (540+ words) Protein nanocages have been growing as a research focus in recent years due to their potential as a platform for next-generation drug delivery systems. These hollow structures, which measure only nanometres in size, are formed when multiple proteins spontaneously bind…...

1+ week, 1+ day ago  (712+ words) GPCRs account for a significant proportion of approved drug targets, yet selectively controlling their activity remains a major challenge. Researchers have now used AI-assisted protein design to create miniproteins capable of activating or inhibiting these receptors, providing an alternative strategy…...

1+ mon, 1+ day ago  (652+ words) The oncogenic protein MYC, overactive in most human cancers, has been discovered to directly repair DNA damage in tumour cells, potentially explaining treatment resistance." A protein long associated with fuelling cancer growth has now been found to help damaged tumour…...

1+ mon, 1+ week ago  (581+ words) A new University of South Florida study examines how AI models predict immune system responses to antigens, offering a framework to evaluate computational tools used in immunotherapy and vaccine development. Artificial intelligence is now a huge tool for scientists in…...

2+ mon, 3+ week ago  (208+ words) University of Adelaide researchers have discovered that CD47, a protein known for helping cancer cells evade immune detection, also directly promotes glioblastoma growth and invasion through a novel molecular pathway involving ROBO2 stabilisation....

1+ mon, 3+ week ago  (603+ words) In the wake of recent government policy aimed at actively replacing animal models in drug discovery, we consider a possible solution to the translational shortfalls of current cellular methodologies for neurodegenerative disease. These drugs demonstrated plaque reduction in transgenic mouse…...

1+ mon, 3+ week ago  (393+ words) Researchers at the University of Texas at Austin have identified a new way to disable antimicrobial resistance in bacteria linked to cystic fibrosis, with potential to improve treatment of persistent infections. Antimicrobial resistance remains one of the most pressing global…...

2+ mon, 1+ week ago  (552+ words) Researchers at Oregon State University have developed a new technique that could change the way'lung cancer'is treated while simultaneously addressing a severe muscle-wasting condition often associated with the disease. The findings'describe how specially engineered lipid nanoparticles can deliver therapeutic genetic…...

2+ mon, 1+ week ago  (146+ words) The role of artificial intelligence (AI) in drug design has fundamentally shifted from a speculative tool to a central pillar of pharmaceutical research and development (R&D). Sino Biological plays a critical role in this evolving landscape by acting as an…...

2+ mon, 2+ week ago  (507+ words) Membrane protein workflows are complex, but they do not have to be. Discover how detergent-free purification, automation and q PCR-based analysis improve reproducibility and simplify workflows. Membrane proteins play a central role in modern therapies, yet they remain among the…...