1+ day, 8+ hour ago  (502+ words) Researchers" newest technologies allow them to discover tiny protein that plays a big role in awakening dormant cells when it"s safe to resume normal operations image: Scientists discovered a new protein, now named SNOR, that helps produce a dormant…...

1+ day, 15+ hour ago  (69+ words) AI generates first complete models of proteins in motion (VIDEO) Eurek Alert! A simulated protein backbone (yellow) is gradually augmented with AI-generated snapshots from the LD-FPG, representing side chain positions and dynamic movements. LPCE LTS2 EPFL CC BY SA Credit must…...

1+ day, 15+ hour ago  (351+ words) EPFL researchers have used a neural network to create all-atom models of proteins, as well as the dynamic movements that govern their function. Their comprehensive yet simplified approach resolves a major bottleneck in biology video: A simulated protein backbone (yellow)…...

2+ day, 15+ hour ago  (523+ words) A new layer of control in protein degradation Until now, however, most degraders have relied on a single ligase. This creates a vulnerability: if cells lose or alter that pathway, for example through mutation or adaptation in cancer, the drug…...

2+ day, 14+ hour ago  (281+ words) image: Deep AFM is a deep learning-based method that analyzes high-speed atomic force microscopy images of proteins. It removes noise and identifies protein shapes, enabling accurate detection of transitions between closed and wide-open states during protein function. view more Associate…...

3+ day, 4+ hour ago  (257+ words) Discovery reveals a novel cellular process that protects against liver disease caused by toxic protein buildup image: Researchers at Wash U Medicine have identified a previously unknown biological process that may help explain why only a subset of patients with…...

3+ day, 4+ hour ago  (82+ words) Eurek Alert! Design and characterization of the LIDAPE platform Credit: HIGHER EDUCATON PRESS While genome editing technologies have revolutionized biology, a key gap remains: the lack of methods for direct, site-specific single amino acid editing in endogenous proteins. The ability…...

3+ day, 6+ hour ago  (172+ words) Protein structures (IMAGE) Eurek Alert! An almost perfect match: Two protein subunit structures, one from a gut bacterium and one from a marine relative, overlaid on top of each other. The striking overlap reveals how conserved this protein is across…...

6+ day, 20+ hour ago  (132+ words) DNA helicase HELQ promotes replication fork reversal, protecting cells from toxic DNA crosslinks image: A representative figure showing that HELQ-deficient cells fail to undergo normal fork slowing after MMC (a crosslinking agent) treatment, consistent with defective fork reversal. view more…...

1+ week, 6+ hour ago  (34+ words) (IMAGE) Eurek Alert! Qiang Zhang et al. / corresponding authors Haofen Wang and Huajun Chen. Yan He Dongguan Institute of Materials Science and Technology, CAS heyan@dimst. ac. cn...